diff --git a/drivers/tty/serial/serial_core.c b/drivers/tty/serial/serial_core.c
index ff85ebd3a007..25a83820927a 100644
--- a/drivers/tty/serial/serial_core.c
+++ b/drivers/tty/serial/serial_core.c
@@ -156,7 +156,7 @@ static void __uart_start(struct uart_state *state)
 	 * enabled, serial_port_runtime_resume() calls start_tx() again
 	 * after enabling the device.
 	 */
-	if (pm_runtime_active(&port_dev->dev))
+	if (!pm_runtime_enabled(port->dev) || pm_runtime_active(&port_dev->dev))
 		port->ops->start_tx(port);
 	pm_runtime_mark_last_busy(&port_dev->dev);
 	pm_runtime_put_autosuspend(&port_dev->dev);