diff --git a/drivers/bluetooth/hci_qca.c b/drivers/bluetooth/hci_qca.c
index 92fa20f5ac7d..94c85f4fbf3b 100644
--- a/drivers/bluetooth/hci_qca.c
+++ b/drivers/bluetooth/hci_qca.c
@@ -1672,6 +1672,9 @@ static bool qca_wakeup(struct hci_dev *hdev)
 	struct hci_uart *hu = hci_get_drvdata(hdev);
 	bool wakeup;
 
+	if (!hu->serdev)
+		return true;
+
 	/* BT SoC attached through the serial bus is handled by the serdev driver.
 	 * So we need to use the device handle of the serdev driver to get the
 	 * status of device may wakeup.