diff --git a/drivers/i2c/busses/i2c-qcom-geni.c b/drivers/i2c/busses/i2c-qcom-geni.c
index 8b4c35f47a70..dce75b85253c 100644
--- a/drivers/i2c/busses/i2c-qcom-geni.c
+++ b/drivers/i2c/busses/i2c-qcom-geni.c
@@ -366,6 +366,7 @@ static int geni_i2c_rx_one_msg(struct geni_i2c_dev *gi2c, struct i2c_msg *msg,
 		geni_se_select_mode(se, GENI_SE_FIFO);
 
 	writel_relaxed(len, se->base + SE_I2C_RX_TRANS_LEN);
+	geni_se_setup_m_cmd(se, I2C_READ, m_param);
 
 	if (dma_buf && geni_se_rx_dma_prep(se, dma_buf, len, &rx_dma)) {
 		geni_se_select_mode(se, GENI_SE_FIFO);
@@ -373,8 +374,6 @@ static int geni_i2c_rx_one_msg(struct geni_i2c_dev *gi2c, struct i2c_msg *msg,
 		dma_buf = NULL;
 	}
 
-	geni_se_setup_m_cmd(se, I2C_READ, m_param);
-
 	time_left = wait_for_completion_timeout(&gi2c->done, XFER_TIMEOUT);
 	if (!time_left)
 		geni_i2c_abort_xfer(gi2c);
@@ -408,6 +407,7 @@ static int geni_i2c_tx_one_msg(struct geni_i2c_dev *gi2c, struct i2c_msg *msg,
 		geni_se_select_mode(se, GENI_SE_FIFO);
 
 	writel_relaxed(len, se->base + SE_I2C_TX_TRANS_LEN);
+	geni_se_setup_m_cmd(se, I2C_WRITE, m_param);
 
 	if (dma_buf && geni_se_tx_dma_prep(se, dma_buf, len, &tx_dma)) {
 		geni_se_select_mode(se, GENI_SE_FIFO);
@@ -415,8 +415,6 @@ static int geni_i2c_tx_one_msg(struct geni_i2c_dev *gi2c, struct i2c_msg *msg,
 		dma_buf = NULL;
 	}
 
-	geni_se_setup_m_cmd(se, I2C_WRITE, m_param);
-
 	if (!dma_buf) /* Get FIFO IRQ */
 		writel_relaxed(1, se->base + SE_GENI_TX_WATERMARK_REG);
 
diff --git a/drivers/soc/qcom/qcom-geni-se.c b/drivers/soc/qcom/qcom-geni-se.c
index d0e4f520cff8..7649b2057b9a 100644
--- a/drivers/soc/qcom/qcom-geni-se.c
+++ b/drivers/soc/qcom/qcom-geni-se.c
@@ -266,36 +266,63 @@ EXPORT_SYMBOL(geni_se_init);
 static void geni_se_select_fifo_mode(struct geni_se *se)
 {
 	u32 proto = geni_se_read_proto(se);
-	u32 val;
+	u32 val, val_old;
 
 	geni_se_irq_clear(se);
 
-	val = readl_relaxed(se->base + SE_GENI_M_IRQ_EN);
+	/*
+	 * The RX path for the UART is asynchronous and so needs more
+	 * complex logic for enabling / disabling its interrupts.
+	 *
+	 * Specific notes:
+	 * - The done and TX-related interrupts are managed manually.
+	 * - We don't RX from the main sequencer (we use the secondary) so
+	 *   we don't need the RX-related interrupts enabled in the main
+	 *   sequencer for UART.
+	 */
 	if (proto != GENI_SE_UART) {
+		val_old = val = readl_relaxed(se->base + SE_GENI_M_IRQ_EN);
 		val |= M_CMD_DONE_EN | M_TX_FIFO_WATERMARK_EN;
 		val |= M_RX_FIFO_WATERMARK_EN | M_RX_FIFO_LAST_EN;
-	}
-	writel_relaxed(val, se->base + SE_GENI_M_IRQ_EN);
+		if (val != val_old)
+			writel_relaxed(val, se->base + SE_GENI_M_IRQ_EN);
 
-	val = readl_relaxed(se->base + SE_GENI_S_IRQ_EN);
-	if (proto != GENI_SE_UART)
+		val_old = val = readl_relaxed(se->base + SE_GENI_S_IRQ_EN);
 		val |= S_CMD_DONE_EN;
-	writel_relaxed(val, se->base + SE_GENI_S_IRQ_EN);
+		if (val != val_old)
+			writel_relaxed(val, se->base + SE_GENI_S_IRQ_EN);
+	}
 
-	val = readl_relaxed(se->base + SE_GENI_DMA_MODE_EN);
+	val_old = val = readl_relaxed(se->base + SE_GENI_DMA_MODE_EN);
 	val &= ~GENI_DMA_MODE_EN;
-	writel_relaxed(val, se->base + SE_GENI_DMA_MODE_EN);
+	if (val != val_old)
+		writel_relaxed(val, se->base + SE_GENI_DMA_MODE_EN);
 }
 
 static void geni_se_select_dma_mode(struct geni_se *se)
 {
-	u32 val;
+	u32 proto = geni_se_read_proto(se);
+	u32 val, val_old;
 
 	geni_se_irq_clear(se);
 
-	val = readl_relaxed(se->base + SE_GENI_DMA_MODE_EN);
+	if (proto != GENI_SE_UART) {
+		val_old = val = readl_relaxed(se->base + SE_GENI_M_IRQ_EN);
+		val &= ~(M_CMD_DONE_EN | M_TX_FIFO_WATERMARK_EN);
+		val &= ~(M_RX_FIFO_WATERMARK_EN | M_RX_FIFO_LAST_EN);
+		if (val != val_old)
+			writel_relaxed(val, se->base + SE_GENI_M_IRQ_EN);
+
+		val_old = val = readl_relaxed(se->base + SE_GENI_S_IRQ_EN);
+		val &= ~S_CMD_DONE_EN;
+		if (val != val_old)
+			writel_relaxed(val, se->base + SE_GENI_S_IRQ_EN);
+	}
+
+	val_old = val = readl_relaxed(se->base + SE_GENI_DMA_MODE_EN);
 	val |= GENI_DMA_MODE_EN;
-	writel_relaxed(val, se->base + SE_GENI_DMA_MODE_EN);
+	if (val != val_old)
+		writel_relaxed(val, se->base + SE_GENI_DMA_MODE_EN);
 }
 
 /**
@@ -651,7 +678,7 @@ int geni_se_tx_dma_prep(struct geni_se *se, void *buf, size_t len,
 	writel_relaxed(lower_32_bits(*iova), se->base + SE_DMA_TX_PTR_L);
 	writel_relaxed(upper_32_bits(*iova), se->base + SE_DMA_TX_PTR_H);
 	writel_relaxed(GENI_SE_DMA_EOT_BUF, se->base + SE_DMA_TX_ATTR);
-	writel_relaxed(len, se->base + SE_DMA_TX_LEN);
+	writel(len, se->base + SE_DMA_TX_LEN);
 	return 0;
 }
 EXPORT_SYMBOL(geni_se_tx_dma_prep);
@@ -688,7 +715,7 @@ int geni_se_rx_dma_prep(struct geni_se *se, void *buf, size_t len,
 	writel_relaxed(upper_32_bits(*iova), se->base + SE_DMA_RX_PTR_H);
 	/* RX does not have EOT buffer type bit. So just reset RX_ATTR */
 	writel_relaxed(0, se->base + SE_DMA_RX_ATTR);
-	writel_relaxed(len, se->base + SE_DMA_RX_LEN);
+	writel(len, se->base + SE_DMA_RX_LEN);
 	return 0;
 }
 EXPORT_SYMBOL(geni_se_rx_dma_prep);