diff --git a/arch/x86/oprofile/nmi_int.c b/arch/x86/oprofile/nmi_int.c
index 174c59774cc9..a7a7677265b6 100644
--- a/arch/x86/oprofile/nmi_int.c
+++ b/arch/x86/oprofile/nmi_int.c
@@ -460,7 +460,7 @@ static int nmi_setup(void)
 		goto fail;
 
 	for_each_possible_cpu(cpu) {
-		if (!cpu)
+		if (!IS_ENABLED(CONFIG_SMP) || !cpu)
 			continue;
 
 		memcpy(per_cpu(cpu_msrs, cpu).counters,