diff --git a/net/ipv6/ip6_output.c b/net/ipv6/ip6_output.c
index b6a94ff0bbd0..e164684456df 100644
--- a/net/ipv6/ip6_output.c
+++ b/net/ipv6/ip6_output.c
@@ -1021,6 +1021,9 @@ static int ip6_dst_lookup_tail(struct net *net, const struct sock *sk,
 		}
 	}
 #endif
+	if (ipv6_addr_v4mapped(&fl6->saddr) &&
+	    !(ipv6_addr_v4mapped(&fl6->daddr) || ipv6_addr_any(&fl6->daddr)))
+		return -EAFNOSUPPORT;
 
 	return 0;